Card Category
Upgrade Priority Cards
Cards that benefit most from upgrading in Slay the Spire 2 — maximize your campfire efficiency with these upgrade targets.
Choosing which cards to upgrade at campfires is one of the most important decisions in Slay the Spire 2. With limited upgrade opportunities — typically 4-7 per run — selecting the right cards to upgrade can significantly impact your success rate. This category highlights cards whose upgrades provide the most value.
Upgrades generally fall into three categories: numerical improvements (more damage, more block), mechanical improvements (reduced cost, added effects), and enabling upgrades (turning a good card into an excellent one). The best upgrades are those that change how a card functions, not just by how much.
Cost reduction upgrades are among the most valuable. Cards like Corruption and Wraith Form that cost 3 energy become much easier to play when upgraded to cost 2 or retain. Upgrades that add card draw or generate additional resources also provide outsized value, as they improve your deck's consistency as well as individual card power.
Each character has priority upgrade targets. For the Ironclad, upgrading Bash (3 Vulnerable instead of 2) is almost always correct. The Silent's Survivor upgrade (+3 block) and Neutralize upgrade (+1 Weak on application) provide excellent early-game value. The Defect's Zap upgrade (Innate) and Dualcast upgrade (+damage) are high priority.
Consider your deck's specific needs when upgrading. If you lack AOE, upgrading a Whirlwind or Electrodynamics may be better than upgrading a single-target card. If you're struggling with defense, upgrading your best block card may be the right call.

Abrasive
Rare · Power · Silent
Gain 1 Dexterity. Gain 4 Thorns.

Accelerant
Rare · Power · Silent
Poison is triggered 1 additional time.

Accuracy
Uncommon · Power · Silent
Shivs deal 4 additional damage.

Acrobatics
Common · Skill · Silent
Draw 3 cards. Discard 1 card.

Adaptive Strike
Rare · Attack · Defect
Deal 18 damage. Add a 0 copy of this card into your Discard Pile.

Adrenaline
Rare · Skill · Silent
Gain . Draw 2 cards.

Afterimage
Rare · Power · Silent
Whenever you play a card, gain 1 Block.

Afterlife
Common · Skill · Necrobinder
Summon 6.

Aggression
Rare · Power · Ironclad
At the start of your turn, put a random Attack from your Discard Pile into your Hand and Upgrade it.

Alchemize
Rare · Skill · Colorless
Procure a random potion.

Alignment
Uncommon · Skill · Regent
Gain .

All for One
Rare · Attack · Defect
Deal 10 damage. Put ALL 0 cards from your Discard Pile into your Hand.

Anger
Common · Attack · Ironclad
Deal 6 damage. Add a copy of this card into your Discard Pile.

Anointed
Rare · Skill · Colorless
Put every Rare card from your Draw Pile into your Hand.

Anticipate
Common · Skill · Silent
Gain 3 Dexterity this turn.

Apotheosis
Ancient · Skill · event
Upgrade ALL your cards.

Apparition
Ancient · Skill · event
Gain 1 Intangible.

Armaments
Common · Skill · Ironclad
Gain 5 Block. Upgrade a card in your Hand.

Arsenal
Rare · Power · Regent
Whenever you play a Colorless card, gain 1 Strength.

Ascender's Bane
Curse · Curse · curse