Slay the Spire 2 Wiki & Guide
Slay the Spire 2 Wiki, Cards, Builds & Strategy Guides
Complete STS2 resource — card database, relic catalog, character guides, deck builds, tier lists, and tools for every run.
Quickly look up STS2 card text, character pools, notable relics, boss mechanics, and practical build directions. Built for in-run lookup and for beginners who want a clear path from character guides to card rankings.
Choose Your Champion
Meet the 5 champions of Slay the Spire 2. Each STS2 character has a unique starting deck, exclusive relics, and specialized mechanics — from the Ironclad's Strength and Exhaust to the Necrobinder's minion armies.
Latest Updates
All →v0.106.0 Patch Guide: Enemy Balance Pass, Defect Adjustments & Mummified Hand Rework
A full breakdown of the v0.106.0 beta patch — Infested Prism rework, Skulking Colony / Aeonglass tweaks, every card change across all five characters, and the new Mummified Hand priority system.
v0.105.0 & v0.105.1 Patch Guide: Aeonglass, Bestiary, and the Bi-Weekly Cadence
A full breakdown of the May 7-8 beta patches — Doormaker removal, the new Aeonglass boss, the first Bestiary build, every meaningful balance change, and the shift to bi-weekly patching.
🆕 Getting Started
New to Slay the Spire 2? Start here.
Beginner First Run Guide
A calm checklist for your first Slay the Spire 2 runs.
Slay the Spire 2 Beginner Guide — Read This Before Your First Run
How a run works, which character to start with, what to practice in your first three games, and where to look things up. A plain-language STS2 starter guide.
10 Beginner Mistakes That End Slay the Spire 2 Runs
Taking every card, hoarding potions, always chasing the greedy route — the most common STS2 beginner mistakes, why they hurt, and what to do instead.
Slay the Spire 2 FAQ — Platforms, Characters, Co-op, and New Mechanics
Quick answers to the questions every new Slay the Spire 2 player asks: where to get it, whether STS1 is required, who the five characters are, co-op, blessings, enchantments, and more.
Relic Tier List: Which Slay the Spire 2 Relics Are Worth a Detour
A relic tier list built on how often a relic helps, not how rare it is: the relics worth a shop detour, the ones that fix a weak turn, and the traps.
🎮 Character Guides
Beginner to advanced guides for all 5 characters
Ironclad Exhaust Engine Deep Dive
Turn exhaust from a mechanic into your primary win condition. Real card analysis for Dark Embrace, Burning Pact, Pact's End, and more.
Silent Poison Strategy — Stacking, Burst, and Scaling
Complete guide to poison: early picks, Catalyst timing, Accelerant synergy, and when to pivot away from poison.
Defect Temporary Focus & Orb Cycling
How STS2 changed Focus to temporary windows, and how to build around it with Hotfix, Focused Strike, Synchronize, and aggressive evoke cycles.
Regent Forge & Resource Economy Guide
How Forge, Stars, and Debris work together. Real card analysis for Big Bang, The Smith, Wrought in War, and the resource loop.
Necrobinder Summon & Soul Synergy
Complete guide to summon types, soul cards, Osty mechanics, and building a board that wins. Based on real STS2 card data.
Defect Orb Deck Guide: Slots, Focus Windows and Evoke Timing
How to build a Defect orb deck in Slay the Spire 2 that still blocks on its bad turns: slots, Focus windows, evoke order, card picks and upgrade order.
🔨 Featured Builds
Proven build directions for every character
Ironclad Strength Tempo
Fast attacks backed by strength scaling.
Silent Poison Build Guide — Cards, Relics, Upgrades & Pathing
Build a winning Silent poison deck in Slay the Spire 2: card picks, relics, upgrade order, act-by-act pathing, combat plans, and common mistakes.
Silent Discard Engine
Turn discard into draw, damage, and defense.
Defect Frost Focus
Scale frost orbs until blocking becomes automatic.
📚 More Resources
Wiki
Mechanics Wiki
Deep dive into Slay the Spire 2 mechanics — Poison damage calculation, Orb channeling priority, Strength scaling, Exhaust synergies, and more. Each STS2 wiki article explains how the system works and how to use it effectively.
Tier List
Card Tier List
S/A/B/C/D card rankings for every character in Slay the Spire 2. Our STS2 tier list helps you identify must-pick cards, situational picks, and cards to skip based on your current build direction.
Tools
Game Helpers
Reward Helper, Build Planner (soon)
Why STS2.INFO?
STS2.INFO is a complete Slay the Spire 2 resource built by players for players. The STS2 card database includes every Attack, Skill, and Power with detailed stats and upgrade comparisons. The STS2 tier list ranks all cards from S-tier to D-tier with character-specific context. Our Slay the Spire 2 guides cover beginner checklists, character strategies, and advanced techniques. Build directions include core card lists, relic recommendations, and tier rankings. All Slay the Spire 2 data is sourced directly from the game through Spire Codex to ensure accuracy.
▶️Find STS2 video guides on YouTubeFAQ
Is STS2 harder than STS1?▾
Energy is more scarce, enemies scale faster, and status effects hit harder — but cards are stronger and new mechanics compensate. Different, not strictly harder.
Best starter character?▾
Ironclad is most forgiving — high HP, straightforward strength scaling, clear exhaust synergy. Silent is also good. Save Regent and Necrobinder for after you understand the basics.
What can I look up on STS2.INFO?▾
Use STS2.INFO to look up Slay the Spire 2 cards, relics, characters, bosses, monsters, build ideas, and card tier rankings. The homepage prioritizes fast paths into the card database, build library, and beginner guides.
💎 Notable Relics
All Relics →Akabeko
At the start of each combat, gain 8 Vigor.
UncommonIncreases gold for more shopping power
Alchemical Coffer
Upon pickup, gain 4 potion slots filled with random potions.
AncientPowerful relic that shapes your build direction
Arcane Scroll
Upon pickup, obtain a random Rare Card to add to your Deck.
AncientIncreases card draw for hand advantage
Archaic Tooth
Upon pickup, Transform a starter card with an ancient version.
AncientIncreases card draw for hand advantage