Strategy Guides
Slay the Spire 2 Guides
Practical guides for pathing, card rewards, potions, campfires, and character starts. Written for real run decisions, not generic wiki filler.
Beginner · Beginner · 7 min
Beginner First Run Guide
A calm checklist for your first Slay the Spire 2 runs.
Beginner · Beginner · 6 min
Map Pathing: When to Take Elites
How to read routes, fires, shops, and elite fights.
Beginner · Beginner · 8 min
Card Reward Priority
A simple method for choosing between three cards.
Beginner · Beginner · 5 min
Potions Win Elite Fights
When to save, buy, or spend potions.
Beginner · Beginner · 6 min
Upgrade or Rest?
A practical campfire decision rule.
Character · Beginner · 8 min
Ironclad Starter Guide
Damage, block, exhaust, and strength for Ironclad runs.
Character · Beginner · 8 min
Silent Starter Guide
Poison, draw, discard, and defense for Silent runs.
Character · Beginner · 8 min
Defect Starter Guide
Orbs, focus, powers, and pacing for Defect runs.
Character · Intermediate · 8 min
Regent Starter Guide
A practical starting framework for Regent decks.
Character · Intermediate · 8 min
Necrobinder Starter Guide
How to build around summons, sacrifice, and value turns.
Character · Beginner · 7 min
Regent Beginner Guide
A practical first-run framework for the cosmic ruler.
Character · Beginner · 7 min
Necrobinder Beginner Guide
How to start winning with summons and sacrifice.
Advanced · Intermediate · 10 min
Act 1 Pathing and Elite Strategy
Boss-specific preparation, elite gauntlet planning, and potion management.
Advanced · Beginner · 7 min
Deck Management: When to Skip, When to Remove
The single most important skill in Slay the Spire 2.
Advanced · Intermediate · 8 min
STS2 vs STS1: Key Differences for Veterans
What changed, what stayed, and how to adapt your StS1 instincts.
Character · Intermediate · 10 min
Ironclad Exhaust Engine Deep Dive
Turn exhaust from a mechanic into your primary win condition. Real card analysis for Dark Embrace, Burning Pact, Pact's End, and more.
Character · Intermediate · 10 min
Silent Poison Strategy — Stacking, Burst, and Scaling
Complete guide to poison: early picks, Catalyst timing, Accelerant synergy, and when to pivot away from poison.
Character · Intermediate · 10 min
Defect Temporary Focus & Orb Cycling
How STS2 changed Focus to temporary windows, and how to build around it with Hotfix, Focused Strike, Synchronize, and aggressive evoke cycles.
Character · Intermediate · 10 min
Regent Forge & Resource Economy Guide
How Forge, Stars, and Debris work together. Real card analysis for Big Bang, The Smith, Wrought in War, and the resource loop.
Character · Intermediate · 10 min
Necrobinder Summon & Soul Synergy
Complete guide to summon types, soul cards, Osty mechanics, and building a board that wins. Based on real STS2 card data.
Advanced · Intermediate · 10 min
Act 1 Boss Strategies — Slime Boss, Hexaghost, Guardian
Complete breakdown of all three STS2 Act 1 bosses: what they do, what your deck needs, and which cards to prioritize against each.
Advanced · Intermediate · 9 min
Elite Fighting Guide — When to Fight, When to Skip
Act-by-act breakdown of elite fights in STS2. How to prepare for Act 1, 2, and 3 elites, and the gold/relic math that tells you when to take the risk.
Advanced · Intermediate · 8 min
Enchantment & Clone Guide — Best Cards to Enchant and Clone
Detailed guide to STS2's enchantment system. Which cards deserve the Clone enchantment, how enchantments change card priorities, and what to look for in events.
Advanced · Beginner · 7 min
Ancient Blessings Pick Guide by Character
Which blessings to pick for Ironclad, Silent, Defect, Regent, and Necrobinder — act by act.
Advanced · Intermediate · 10 min
Mid-Game Transition Guide — Surviving Act 2 and Act 3
How to adapt your Act 1 deck for the challenges of Act 2 and Act 3. Draft priorities, blessing choices, and when to pivot your build.